Increasing the quality and reproducibility of biomedical research using chemical probes.

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Welcome to the new Chemical Probes Portal! Experience the new and improved Chemical Probes Portal from

A free, public online resource of expert reviews and evaluations of chemical probes.

The Chemical Probes Portal supports the biological research community to select the best chemical tools such as inhibitors, activators and degraders, to use as chemical probes for their experiments. Its expert panel provides guidance to select the most suitable probe for use in in-vitro and in-vivo experiments and shares experiences in best practice.

If you need to access the old site, it is still available at


The new Chemical Probes Portal is now available at including data and recommendations on more than 650 small molecule tools. The new portal has a faster, more intuitive search, easier online forms for submitting and reviewing compounds and an entirely new backend structure to facilitate updates in the future.

Alle Dinge sind Gift, und nichts ist ohne Gift, allein die Dosis macht dass ein Ding kein Gift ist. (The dose makes the poison.)

Aled Edwards, CEO of the Structural Genomics Consortium.