ATP-competitive inhibitor of MAPK14
Protein target names: MAPK14
Mechanism of action: ATP-competitive inhibitor
Recommended in-cell concentration:
In Vitro Validations
Uniprot ID: Q16539
Target Class: Protein kinase
Target SubClass: CMGC
Potency Value: 2.8 nM
Potency Assay: KD was determined in a kinase binding assay. The IC50 (0.009 uM) was determined using a spectrophotometric coupled-enzyme assay.
PDB ID for probe-target interaction (3D structure): 3FC1
Mitogen-activated protein kinase 14, SAPK2A, MXI2, ...
In Cell Validations
In Vivo Data
I have extra information to add