VPS34-IN-4

VPS34-IN-4 : Inhibitor of PIK3C3

Probe VPS34-IN-4 is in the process of SERP review.

Please continue to check back for new reviews and commentary.

Uniprot ID: Q8NEB9

Target Class: Kinase

Target SubClass: PI3/PI4

Potency: IC50

Potency Value: 15nM

Potency Assay: KinaseGLO assay

PDB ID for probe-target interaction (3D structure): 5ENN

Target aliases:

Phosphatidylinositol 3-kinase catalytic subunit ty ...

Off Target: MAP3K7

Potency end-point : Activity 150nM

Probe Selectivity in Vitro:

Selective over other lipid and protein kinases (>100-fold against >280 kinases evaluated, except TAK1 and PI3Kδ, 10-fold and 40-fold, respectively)".

No SERP comments found for VPS34-IN-4