VERUBECESTAT

VERUBECESTAT : Inhibitor of BACE1, BACE2

Probe VERUBECESTAT is in the process of SERP review.

Please continue to check back for new reviews and commentary.

Uniprot ID: P56817

Target Class: Enzyme

Target SubClass: Peptidase

Potency: Ki

Potency Value: 2.2 nM

Potency Assay: Enzymatic assay (FRET)

PDB ID for probe-target interaction (3D structure): 5HU1

Target aliases:

Beta-secretase 1, KIAA1149, BACE, BACE1, BACE1_HUM ...

Potency assay (off target): Selective against CatD (Ki ≫100,000 nM), CatE (Ki ≫100,000 nM), pepsin (Ki ≫100,000 nM), renin (Ki 33,800nM)

No SERP comments found for VERUBECESTAT