PHENANTHROLINE
Unsuitables - unsuitable to be used as a chemical probe
Structure
This is unsuitable as a chemical probe: While this
compound has been used to interrogate specific protein
targets, it is not a chemical probe and should not be used
in assays that depend on a potent and selective modulator
of the protein.
Non selective compound
Described as a Rpn11 inhibitor, PHENANTHROLINE is known to chelate metals. The inhibitory activity is not specific and is due to sequestration of Zn2+ from the target, hence it should not be used as a chemical probe. (https://www.science.org/content/blog-post/there-are-probes-and-there-are-probes)