Historical Compound - unsuitable to be used as a chemical probe
This is a Historical compound: While this compound has been used to interrogate specific protein targets, it is not a chemical probe and should not be used in assays that depend on a potent and selective modulator of the protein.
Non selective compound
Intended target: BCL2; Gossypol has multiple reported mechanims of action, including agonizing phospholipase A2 and induction of NOXA; Soderquist & Eastman. BCL2 inhibitors as anticancer drugs: a plethora of misleading BH3 mimetics. Mol Cancer Ther. 15, 2011-7 (2016).
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