Tris-DBA palladium
Unsuitables - unsuitable to be used as a chemical probe
Structure
This is unsuitable as a chemical probe: While this
compound has been used to interrogate specific protein
targets, it is not a chemical probe and should not be used
in assays that depend on a potent and selective modulator
of the protein.
Non selective compound
In Kallemeijn W et al 2019 is highlighted the fundamental inability of Tris-DBA palladium to inhibit cellular N-myristoylation while inducing marked cytotoxicity and apoptosis. This evidence invalidates this compound as an NMT inhibitor (PMID: 31006618)
.