SR-0813

Inhibitor of MLLT1, MLLT3

Structure

Information

Protein target names: MLLT1, MLLT3

Mechanism of action: Inhibitor

Recommended in-cell concentration:
up to 1 uM

In Vitro Validations

Uniprot ID: Q03111
Target Class: Epigenetic
Target SubClass: YEATS
Potency: IC 50
Potency Value: 25 nM
Potency Assay: ENL-H3K27cr HTRF
PDB ID for probe-target interaction (3D structure): --
Structure-activity relationship: yes
Target aliases:
Protein ENL, YEATS1, LTG19, ENL, MLLT1, ENL_HUMAN, ...

DOI Reference: 10.1021/acscentsci.0c01550

Uniprot ID: Q03111
Target Class: Epigenetic
Target SubClass: YEATS
Potency: Kd
Potency Value: 30 nM
Potency Assay: SPR
PDB ID for probe-target interaction (3D structure): --
Target aliases:
Protein ENL, YEATS1, LTG19, ENL, MLLT1, ENL_HUMAN, ...

DOI Reference: 10.1021/acscentsci.0c01550

In Cell Validations

In Vivo Data

No in Vivo Validations

I have extra information to add

SERP ratings and comments


No SERP comments found for SR-0813