SB-612111
SB-612111 : NOP antagonist of OPRL1
Structure
In Cells
In Model Organisms
Information
Protein target names: OPRL1
Mechanism of action: NOP antagonist
In Vitro Validations
In Cell Validations
In Vivo Data
SERP ratings and comments
SERP Ratings
SERP Comments:
Note: SB-612111 appears to be slowly reversible. From Spagnolo 2007 “Apart from antagonist potency, the reversibility test conducted in the mouse vas deferens experiments demonstrated another important difference between SB-612111 and (±)J113397. In fact, (±)J-113397 effects could be reversed by washing the tissues, whereas those of SB-612111 were not affected even after 3 h of washing.”
(last updated: 25 Jul 2021 )
SERP Ratings
(last updated: 4 Aug 2021 )
SERP Ratings
(last updated: 5 Aug 2021 )