PFI-6
Inhibitor of MLLT1, MLLT3
Structure
In Cells
(1
ratings)
In Model Organisms
(0
ratings)
note: The Chemical Probes Portal only endorses
compounds as chemical probes for use as specific and
selective modulators of the proposed target if they
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Probe PFI-6 is in the process of SERP review.
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SERP ratings and comments
SERP+ Ratings
In Cell Rating
SERP+ Comments:
Presented potency data at the level <0.2 uM seem to be sufficient to support the application of compound PFI-6 as chemical probe for MLLT1/3. However, the side-by-side comparison with the negative control PFI-6N is recommended. The in vivo and toxicity data were not provided therefore application of PFI-6 in an in vivo setting is currently not recommended.
(last updated: 22 Mar 2023 )