Alex Bullock

University of Oxford

Alex Bullock is Professor of Structural and Chemical Biology at the Centre for Medicines Discovery, University of Oxford. Prior to this, he spent over 15 years as part of the Structural Genomics Consortium (SGC), where his group contributed structures of human protein kinases and E3 ligases. His interests in phosphorylation and ubiquitylation lie primarily with proteins implicated in cancer and rare diseases. This work ranges from fragment screens and chemical probes to a phase II clinical study targeting ALK2 kinase gain of function. Alex received his degree and PhD from the University of Cambridge where he trained with Sir Alan Fersht. He subsequently held a Wellcome Fellowship for positions with David Baker at the University of Washington, Seattle, and later with Sir Peter Ratcliffe at the University of Oxford for work on VHL.