Positive Allosteric Modulator of GPR68



  • GPR68
  • Positive Allosteric Modulator

In Vitro Validations

No in Vitro Validations

In Cell Validations

In Vivo Data

Off-Target Selectivity Assesments

Probe Selectivity in Vitro:

Screened for radioligand binding modulation of CNS GPCRs and toxic pharmacological off-targets. Minimal activity at all targets (pKi > 7)

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SERP ratings and comments

SERP Ratings

In Cell Rating
In Model Organisms

SERP Comments:

Ogerin has moderate affinity at two GPCRs, 5-HT2B and the A2A receptor.

(last updated: 18 Oct 2020 )