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MS4078

MS4078 : Degrader (PROTAC) of ALK

Structure

Information

  • ALK
  • Degrader (PROTAC)
  • 100 nM

In Vitro Validations

Uniprot ID: Q9UM73
Target Class: Kinase
Target SubClass: TK
Potency: Kd
Potency Value: 19 nM
Potency Assay: Competitive binding assay using DNA tag labeled ALK
PDB ID for probe-target interaction (3D structure): --
Target aliases:
ALK tyrosine kinase receptor, ALK, ALK_HUMAN, Anap ...

DOI Reference: 10.1016/j.ejmech.2018.03.071

In Cell Validations

In Vivo Data

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