Menin-MLL PPI inhibitor of KMT2A
Protein target names: KMT2A
Mechanism of action: Menin-MLL PPI inhibitor
In Vitro Validations
Uniprot ID: Q03164
Target Class: Epigenetic
Target SubClass: Protein methyltransferase
Potency Value: 85 nM
Potency Assay: ITC. IC50 data were also reported (56 nM).
PDB ID for probe-target interaction (3D structure): 4GO8
Structure-activity relationship: Yes
Histone-lysine N-methyltransferase 2A, TRX1, MLL1, ...
In Cell Validations
In Vivo Data
No in Vivo Validations
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