Covalent Inhibitor of PSMB9
Protein target names: PSMB9
Mechanism of action: Covalent Inhibitor
In Vitro Validations
Uniprot ID: P28065
Target Class: Protein metabolism
Target SubClass: Proteasome subunit
Potency Value: 51 nM
Potency Assay: In a MOLT-4 (human T cell leukemia) cellular lysate, a proteasome constitutive/immunoproteasome subunit ELISA (ProCISE) was employed for quantitative assessment of subunit-specific activity.
PDB ID for probe-target interaction (3D structure): --
Structure-activity relationship: Yes, please see ACS Med Chem paper for details..
Proteasome subunit beta type-9, RING12, PSMB6i, LM ...
In Cell Validations
In Vivo Data
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