GSK2334470 : Type I Inhibitor of PDPK1
In Vitro Validations
Uniprot ID: O15530
Target Class: Protein kinase
Target SubClass: AGC
Potency Value: 2.5 nM
PDB ID for probe-target interaction (3D structure): --
3-phosphoinositide-dependent protein kinase 1, PDK ...
In Cell Validations
In Vivo Data
Off-Target Selectivity Assesments
Potency assay (off target): GSK2334470 was tested against a panel of 285 kinases and found to be >1,000-fold selective for PDK1, inhibiting only 24 kinases >50% at 10 uM.
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