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FIRSOCOSTAT

FIRSOCOSTAT : Inhibitor of ACACA, ACACB

Structure

Information

  • ACACA
  • ACACB
  • Inhibitor
  • up to 1 μM

In Vitro Validations

Uniprot ID: Q13085
Target Class: Enzyme
Target SubClass: --
Potency: IC50
Potency Value: 2.1 nM
Potency Assay: Luminescent ADP detection assay (ADP-Glo Kinase Assay Kit; Promega)
PDB ID for probe-target interaction (3D structure): --
Target aliases:
Acetyl-CoA carboxylase 1, ACCA, ACAC, ACACA, ACACA ...

DOI Reference: 10.1073/pnas.1520686113

In Cell Validations

In Vivo Data

Off-Target Selectivity Assesments

Potency assay (off target): >10 μM
Probe Selectivity in Vitro:
Ricera DrugMatrix Panel (101 receptors, GFs, transporters, and ion channels). Data available in SI of DOI: 10.1073/pnas.1520686113
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