ERD-308

ERD-308 : Degrader (PROTAC) of ESR1

Structure

SERP Rating

In Cells

(2 ratings)

In Model Organisms

(0 ratings)

note: The Chemical Probes Portal only endorses compounds as chemical probes for use as specific and selective modulators of the proposed target if they receive three or more (3-4) stars.

Probe ERD-308 is in the process of SERP review.

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Information

ESR1

Degrader (PROTAC)

up to 100 nM

Probe Availability:

MedChemExpress
MCULE

In Vitro Validations

No in Vitro Validations

In Cell Validations

In Vivo Data

No in Vivo Validations

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SERP ratings and comments

SERP Ratings

In Cell Rating

(last updated: 21 Apr 2022 )

SERP+ Ratings

In Cell Rating

SERP+ Comments:

There is no selectivity evaluation by proteomics. in particular, the existence of estrogen receptor B, requires its inclusion in the degradation analysis.

(last updated: 31 Oct 2024 )