CDK11-In-37

CDK11-In-37 : Inhibitor of CDK11A, CDK11B

Structure

Information

  • CDK11A
  • CDK11B
  • Inhibitor
  • up to 1 uM

In Vitro Validations

No in Vitro Validations

In Cell Validations

In Vivo Data

Off-Target Selectivity Assesments

Potency assay (off target): KinomeSCAN
Probe Selectivity in Vitro:
Highly selective CDK11 inhibitor against other kinases in an extended kinase panel profiling (>100 kinases examined in KINOMEscan panel).
Potency assay, off target (cells): NanoBRET
Probe Selectivity in Cell:
Selective against CDK7 (50x) and CDK9 (IC50 >10 uM)
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SERP ratings and comments


No SERP comments found for CDK11-In-37