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CDD-1653

CDD-1653 : Inhibitor of BMPR2

Structure

Information

  • BMPR2
  • Inhibitor
  • up to 25 uM

In Vitro Validations

Uniprot ID: Q13873
Target Class: Kinase
Target SubClass: TKL
Potency: IC50
Potency Value: 2.8 nM
Potency Assay: Kinase-Glo Assay using recombinant BMPR2
PDB ID for probe-target interaction (3D structure): --
Target aliases:
Bone morphogenetic protein receptor type-2, PPH1, ...

DOI Reference: 10.1021/acs.jmedchem.2c01886

In Cell Validations

In Vivo Data

No in Vivo Validations

Off-Target Selectivity Assesments

Potency assay (off target): KinomeSCAN @ 1 uM against 403 kinases with closest off-target ALK1 >1000 nM
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SERP ratings and comments

No SERP comments found for CDD-1653