CCT251455

CCT251455 : Inhibitor of TTK

Structure

Information

  • TTK
  • Inhibitor
  • up to 1 uM

In Vitro Validations

Uniprot ID: P33981
Target Class: Kinase
Target SubClass: Ser/Thr Kinase
Potency: IC50
Potency Value: 3 nM
Potency Assay: Biochemical Assay
PDB ID for probe-target interaction (3D structure): 4C4J
Target aliases:
Dual specificity protein kinase TTK, MPS1L1, MPS1, ...

DOI Reference: 10.1021/jm401395s

In Cell Validations

In Vivo Data

Off-Target Selectivity Assesments

Probe Selectivity in Vitro:
High selectivity versus kinases tested in a broad kinome profiling panel.
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SERP ratings and comments


No SERP comments found for CCT251455