Browse Probes

Probe Name Protein target Target class Subclass Number of SAB Reviews Avg Rating (In Cell) Avg Rating (In Vivo) Published onsort descending
JQ1 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 3
4.0000
3.0000
13 Jul 2015
CHIR-99021 GSK3A, GSK3B Protein kinase CMGC 3
3.6667
2.6667
16 Jul 2015
Salvinorin A OPRK1 GPCR Opioid receptor 3
3.0000
3.0000
16 Jul 2015
PFI-1 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 3
4.0000
2.6667
16 Jul 2015
I-BET151 BRD2, BRD3, BRD4 Epigenetics Bromodomain 3
2.6667
2.6667
16 Jul 2015
LLY-507 SMYD2 Epigenetics Protein methyltransferase 3
2.0000
0.0000
02 Oct 2015
UNC1999 EZH1, EZH2 Epigenetics Protein methyltransferase 2
3.5000
1.0000
02 Oct 2015
GSK343 EZH2 Epigenetics Protein methyltransferase 3
4.0000
0.0000
02 Oct 2015
EPZ011989 EZH1, EZH2 Epigenetics Protein methyltransferase 3
3.6667
2.6667
02 Oct 2015
OICR-9429 WDR5 Structural protein WD40-repeat proteins 3
4.0000
0.6667
02 Oct 2015
UNC1215 L3MBTL3 Epigenetics Malignant brain tumor Reader 3
4.0000
1.0000
02 Oct 2015
(R)-PFI-2 SETD7 Epigenetics Protein methyltransferase 3
4.0000
0.0000
02 Oct 2015
SGC0946 DOT1L Epigenetics Protein methyltransferase 4
3.7500
0.0000
02 Oct 2015
EPZ-5676 DOT1L Epigenetics Protein methyltransferase 3
3.6667
3.3333
02 Oct 2015
SGC707 PRMT3 Epigenetics Protein methyltransferase 4
3.7500
2.0000
02 Oct 2015
UNC0638 EHMT2, EHMT1 Epigenetics Protein methyltransferase 3
2.3333
1.0000
02 Oct 2015
A-366 EHMT2, EHMT1 Epigenetics Protein methyltransferase 3
4.0000
1.6667
02 Oct 2015
I-CBP112 CREBBP, EP300 Epigenetics Bromodomain 3
3.0000
2.0000
03 Nov 2015
SGC-CBP30 CREBBP, EP300 Epigenetics Bromodomain 3
3.3333
0.0000
03 Nov 2015
GSK-J4 KDM6A, KDM6B Epigenetics Lysine demethylase 3
3.3333
1.0000
04 Nov 2015
EPZ020411 PRMT6 Epigenetics Protein methyltransferase 3
2.6667
2.6667
05 Nov 2015
MS023 PRMT1, PRMT3, PRMT4, PRMT6, PRMT8 Epigenetics Protein methyltransferase 3
4.0000
0.0000
05 Nov 2015
BAY-598 SMYD2 Epigenetics Protein methyltransferase 3
4.0000
4.0000
09 Nov 2015
A-196 KMT5B, KMT5C Epigenetics Protein methyltransferase 3
4.0000
1.0000
09 Nov 2015
GSK484 PADI4 Epigenetics Arginine deaminase 3
3.6667
1.3333
09 Nov 2015
AGI-5198 IDH1 (R132H mutant) Other Dehydrogenase 3
2.0000
1.6667
10 Nov 2015
GSK864 IDH1 (mutant) Other Dehydrogenase 2
3.0000
2.5000
10 Nov 2015
Ruxolitinib JAK1, JAK2 Protein kinase Tyrosine Kinase 3
4.0000
4.0000
10 Dec 2015
Rapamycin MTOR Protein kinase Atypical 3
3.3333
3.0000
10 Dec 2015
SGX-523 MET Protein kinase Tyrosine Kinase 3
3.6667
3.6667
10 Dec 2015
WH-4-023 LCK, SRC Protein kinase Tyrosine Kinase 5
1.8000
0.8000
10 Dec 2015
Imatinib BCR-ABL, PDGFR, KIT Protein kinase Tyrosine kinase 3
1.0000
1.0000
10 Dec 2015
CFI-400945 PLK4 Protein kinase Other 3
1.6667
1.6667
10 Dec 2015
PF-3758309 PAK1, PAK4, PAK5, PAK6 Protein kinase STE 3
3.0000
3.0000
10 Dec 2015
Tofacitinib JAK1, JAK2, JAK3 Protein kinase Tyrosine Kinase 3
3.6667
2.3333
10 Dec 2015
GSK2334470 PDK1 Protein kinase AGC 3
4.0000
2.6667
10 Dec 2015
BIX-02188 MAP2K5 Protein kinase STE 3
3.0000
1.3333
10 Dec 2015
PF3644022 MAPKAPK2 Protein kinase CAMK 3
3.3333
2.3333
10 Dec 2015
WZ4003 NUAK1, NUAK2 Protein kinase CAMK 3
3.0000
0.6667
10 Dec 2015
AZD2014 MTOR Protein kinase Atypical 3
3.6667
4.0000
10 Dec 2015
BI2536 PLK1, PLK2, PLK3 Protein kinase Other 3
2.0000
2.0000
10 Dec 2015
Selumetinib MAP2K1 Protein kinase STE 3
3.3333
3.0000
10 Dec 2015
STO609 CAMKK1, CAMKK2 Protein kinase Other 3
2.6667
0.0000
10 Dec 2015
KU-60019 ATM Protein kinase Atypical 3
2.0000
1.6667
10 Dec 2015
CCT241533 CHEK2 Protein kinase CAMK 3
3.6667
0.6667
10 Dec 2015
AC220 FLT3 Protein kinase Tyrosine Kinase 3
3.3333
2.6667
10 Dec 2015
URMC-099 MLK1, MLK2, MLK3 Protein kinase TKL 3
1.3333
1.3333
10 Dec 2015
HG-9-91-01 SIK1, SIK2, SIK3 Protein kinase CAMK 3
3.0000
1.6667
10 Dec 2015
BI-D1870 RPS6KA1, RPS6KA2, RPS6KA3, RPS6KA6 Protein kinase AGC 3
2.0000
0.3333
10 Dec 2015
GNE7915 LRRK2 Protein kinase TKL 3
3.0000
3.0000
10 Dec 2015
NVP-AEW541 IGF1R Protein kinase Tyrosine Kinase 3
3.3333
3.0000
10 Dec 2015
THZ1 CDK7 Protein kinase CMGC 3
3.3333
3.0000
10 Dec 2015
BGJ-398 FGFR1, FGFR2, FGFR3, FGFR4 Protein kinase Tyrosine Kinase 3
3.6667
3.3333
10 Dec 2015
JNK-IN-8 MAPK8, MAPK9, MAPK10 Protein kinase CMGC 3
3.3333
0.6667
10 Dec 2015
P505-15 SYK Protein kinase Tyrosine Kinase 3
3.6667
3.6667
10 Dec 2015
BYL-719 PIK3CA Lipid kinase Class I 3
4.0000
4.0000
10 Dec 2015
AMG900 AURKA, AURKB, AURKC Protein kinase Other 3
3.6667
3.6667
10 Dec 2015
Pictilisib PIK3CA, PIK3CD Lipid kinase Class I 4
2.7500
2.5000
10 Dec 2015
MPS1-IN-1 MPS1 Protein kinase Other 3
2.6667
0.6667
10 Dec 2015
CP-724714 ERBB2 Protein kinase Tyrosine kinase 3
4.0000
4.0000
10 Dec 2015
AZ191 DYRK1B Protein kinase CMGC 3
3.0000
0.0000
10 Dec 2015
AZD1152 AURKB Protein kinase Other 3
3.6667
3.6667
10 Dec 2015
CX-4945 CSNK2A1 Protein kinase CMGC 3
2.3333
2.0000
10 Dec 2015
PF-477736 CHEK1 Protein kinase CAMK 3
3.6667
3.6667
10 Dec 2015
DDR1-IN-1 DDR1 Protein kinase Tyrosine Kinase 3
2.6667
0.6667
10 Dec 2015
CH5424802 ALK Protein kinase Tyrosine kinase 3
4.0000
4.0000
10 Dec 2015
BMS-265246 CDK, CDK2 Protein kinase CMGC 3
2.0000
0.6667
10 Dec 2015
CP-673451 PDGFRbeta Protein kinase Tyrosine kinase 3
2.3333
1.6667
10 Dec 2015
Afatinib EGFR, ERBB2 Protein kinase Tyrosine Kinase 3
2.6667
2.6667
10 Dec 2015
VE-821 ATR Protein kinase Atypical 3
2.6667
0.0000
10 Dec 2015
Bafetinib BCR-ABL, LYN Protein kinase Tyrosine Kinase 4
2.7500
2.5000
10 Dec 2015
AVL-292 BTK Protein kinase Tyrosine kinase 3
2.6667
2.3333
10 Dec 2015
PF-4800567 CSNK1E Protein kinase CK1 3
2.0000
0.6667
10 Dec 2015
MK-5108 AURKA Protein kinase Other 3
4.0000
4.0000
10 Dec 2015
XMD8-92 MAPK7 Protein kinase CMGC 3
2.6667
1.0000
10 Dec 2015
CGI1746 BTK Protein kinase Tyrosine kinase 3
4.0000
4.0000
10 Dec 2015
KH-CB19 CLK1, CLK4, DYRK1A Protein kinase CMGC 3
3.0000
0.6667
10 Dec 2015
SCH772984 MAPK1, MAPK3 Protein kinase CMGC 3
4.0000
3.3333
10 Dec 2015
TX1-85-1 ERBB3 Protein kinase Tyrosine kinase 3
1.6667
0.0000
10 Dec 2015
VX-745 MAPK14 Protein kinase CMGC 3
4.0000
3.6667
10 Dec 2015
BMX-IN-1 BMX Protein kinase Tyrosine kinase 3
3.0000
0.0000
10 Dec 2015
GDC-0879 BRAF V600E Protein kinase TKL 3
3.6667
1.6667
10 Dec 2015
PD0332991 CDK4, CDK6 Protein kinase CMGC 3
4.0000
3.0000
10 Dec 2015
GNF-5 BCR-ABL Protein kinase Tyrosine kinase 3
3.6667
3.3333
10 Dec 2015
EPZ015666 PRMT5 Epigenetics Protein methyltransferase 3
4.0000
4.0000
25 Jan 2016
GSK591 PRMT5 Epigenetics Protein methyltransferase 3
3.3333
1.3333
25 Jan 2016
ABPA3 UBA1, UBA3 Other post-translational modification E1 enzyme 3
2.0000
1.3333
29 Jul 2016
AZ0108 PARP1, PARP2, PARP6 Other post-translational modification PARP 3
2.6667
2.0000
29 Jul 2016
AZ6102 TNKS, TNKS2 Other post-translational modification PARP 3
3.0000
2.0000
29 Jul 2016
BAZ2-ICR BAZ2A, BAZ2B Epigenetics Bromodomain 3
3.0000
1.3333
29 Jul 2016
BI-9564 BRD9, BRD7 Epigenetics Bromodomain 3
3.0000
3.0000
29 Jul 2016
BMS-911543 JAK2 Protein kinase Tyrosine kinase 3
3.6667
3.6667
29 Jul 2016
E7449 PARP1, PARP2, TNKS, TNKS2 Other post-translational modification PARP 3
3.0000
3.0000
29 Jul 2016
GSK2801 BAZ2A, BAZ2B Epigenetics Bromodomain 3
2.3333
1.3333
29 Jul 2016
I-BRD9 BRD9 Epigenetics Bromodomain 3
3.0000
0.0000
29 Jul 2016
JQEZ5 EZH2 Epigenetics Protein methyltransferase 3
2.0000
2.3333
29 Jul 2016
JW55 TNKS, TNKS2 Other post-translational modification PARP 3
1.0000
0.3333
29 Jul 2016
Niraparib PARP1, PARP2 Other post-translational modification PARP 3
4.0000
3.6667
29 Jul 2016
Olaparib PARPs Other post-translational modification PARP 3
3.0000
3.0000
29 Jul 2016
Talazoparib PARPs Other post-translational modification PARP 3
3.3333
3.6667
29 Jul 2016
Veliparib PARP1, PARP2 Other post-translational modification PARP 3
4.0000
2.6667
29 Jul 2016
XAV939 TNKS, TNKS2, PARP1, PARP2 Other post-translational modification PARP 3
1.3333
0.0000
29 Jul 2016
LP99 BRD7, BRD9 Epigenetics Bromodomain 3
2.0000
0.0000
29 Jul 2016
EPZ004777 DOT1L Epigenetics Protein Methyltransferase 3
4.0000
0.3333
08 Aug 2016
BIX-01294 EHMT2 Epigenetics Protein methyltransferase 3
1.6667
1.0000
08 Aug 2016
EI1 EZH2 Epigenetics Protein methyltransferase 3
3.6667
1.3333
08 Aug 2016
DS-437 PRMT5, PRMT7 Epigenetics Protein methyltransferase 3
2.0000
0.3333
08 Aug 2016
MIV-6R KMT2A Epigenetics Protein methyltransferase 3
2.3333
0.6667
08 Aug 2016
CPI-169 EZH1, EZH2 Epigenetics Protein methyltransferase 3
4.0000
2.3333
08 Aug 2016
EPZ-6438 EZH2 Epigenetics Protein Methyltransferase 3
3.3333
2.3333
08 Aug 2016
UNC0642 EHMT2, EHMT1 Epigenetics Protein methyltransferase 3
4.0000
2.6667
08 Aug 2016
CPI-360 EZH2 Epigenetics Protein methyltransferase 3
4.0000
2.3333
08 Aug 2016
CCT244747 CHEK1 Protein kinase CAMK 3
3.3333
3.0000
09 Sep 2016
UNC3866 CBX7, CBX4 Epigenetics Methyl-lysine reader 3
2.6667
0.0000
09 Sep 2016
JAK3i JAK3 Protein kinase Tyrosine kinase 3
2.3333
2.3333
09 Sep 2016
Cortistatin A CDK8, CDK19 Protein kinase CMGC 3
1.6667
1.0000
09 Sep 2016
ML323 USP1, WDR48 Other post-translational modification Deubiquitinase 3
3.3333
0.0000
14 Oct 2016
RSL3 GPX4 Lipid metabolism Glutathione Peroxidase 3
2.3333
2.0000
14 Oct 2016
eCF309 MTOR Protein kinase Atypical 3
3.0000
0.0000
17 Oct 2016
PDD00017273 PARG DNA replication & repair enzyme Glycohydrolase 3
3.3333
0.3333
18 Oct 2016
MT1 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 3
4.0000
4.0000
04 Nov 2016
VH298 VHL Other post-translational modification E3 ubiquitin ligase 3
3.6667
0.0000
15 Nov 2016
MZ1 BRD4 Epigenetics Bromodomain 4
3.5000
0.0000
18 Nov 2016
G-5555 PAK1, PAK2, PAK3 Protein kinase STE 3
3.6667
2.6667
29 Nov 2016
NVS-PAK1-1 PAK1 Protein kinase STE 3
3.6667
1.3333
29 Nov 2016
AX15836 MAPK7 Protein kinase CMGC 3
4.0000
0.6667
05 Dec 2016
AMG-18 ERN1 Protein kinase Other 3
3.3333
2.0000
08 Dec 2016
BiBET BRD4, BRD3, BRD2, BRDT Epigenetics Bromodomain 3
3.3333
0.6667
12 Dec 2016
CCT251545 CDK8, CDK19 Protein kinase CMGC 3
4.0000
3.3333
13 Jan 2017
CCT251236 PIR Other Cupin 2
4.0000
3.0000
17 Jan 2017
NI-42 BRPF1, BRD1, BRPF3 Epigenetics Bromodomain 3
1.6667
1.6667
30 Jan 2017
A-395 EED Epigenetics Polycomb family 3
3.6667
2.0000
31 Jan 2017
Englerin A TRPC4, TRPC5 Ion channel Transient receptor potential channels 3
2.0000
0.3333
31 Jan 2017
Filgotinib JAK1 Protein kinase Tyrosine kinase 3
3.3333
3.6667
10 Feb 2017
GSK481 RIPK1 Protein kinase Ser/Thr Protein Kinase 3
4.0000
0.0000
16 Feb 2017
eCF506 SRC Protein kinase Tyrosine kinase 4
3.0000
2.2500
23 Feb 2017
PFI-3 SMARCA2, SMARCA4, PBRM1 Epigenetics Bromodomain 2
4.0000
1.0000
07 Mar 2017
Venetoclax BCL2 Other Protein Phosphatase 3
4.0000
4.0000
07 Mar 2017
GSK583 RIPK2 Protein kinase AGC 3
3.6667
3.3333
09 Mar 2017
GSK4027 PCAF, GCN5 Epigenetics Bromodomain 5
3.8000
1.4000
13 Mar 2017
L-Moses PCAF, GCN5 Epigenetics Bromodomain 6
2.5000
0.3333
13 Mar 2017
PF-CBP1 CREBBP Epigenetics Bromodomain 3
3.6667
0.0000
13 Mar 2017
2-MT 63 TEK Protein kinase Tyrosine kinase 3
2.6667
2.6667
13 Mar 2017
BLU9931 FGFR4 Protein kinase Tyrosine kinase 3
3.6667
2.6667
14 Mar 2017
AGI-6780 IDH2 (R140Q mutant) Other Dehydrogenase 3
2.0000
0.3333
14 Mar 2017
Skepinone-L MAPK14 Protein kinase CMGC Ser/Thr protein kinase 3
3.6667
3.0000
15 Mar 2017
EED226 EED Epigenetics Polycomb family 4
3.7500
2.7500
30 Mar 2017
A-1155463 BCLXL Other BCL2 family 3
3.0000
2.6667
04 Apr 2017
A-1210477 MCL1 Other BCL2 family 3
2.6667
1.0000
04 Apr 2017
GSK-5959 BRPF1 Epigenetics Bromodomain 3
2.3333
0.0000
04 Apr 2017
UNC2025 MERTK, FLT3 Protein kinase Tyrosine kinase 3
3.0000
3.0000
06 Apr 2017
RGFP966 HDAC3 Epigenetics HDAC 3
3.0000
3.0000
10 Apr 2017
ACY-738 HDAC6 Epigenetics HDAC 3
3.0000
2.6667
10 Apr 2017
Tubacin HDAC6 Epigenetics HDAC 3
3.3333
2.0000
10 Apr 2017
Romidepsin HDAC1, HDAC2, HDAC3, HDAC8 Epigenetics HDAC 3
3.6667
3.0000
11 Apr 2017
FM-381 JAK3 Protein kinase Tyrosine kinase 3
4.0000
0.0000
24 Apr 2017
S63845 MCL1 Other BCL2 family 2
4.0000
3.0000
24 Apr 2017
CPI-0610 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 3
4.0000
4.0000
24 Apr 2017
CPI-637 CREBBP, EP300 Epigenetics Bromodomain 3
2.3333
0.0000
25 Apr 2017
GPR40ant39 FFAR1 GPCR Free fatty acid receptors 3
2.3333
2.0000
10 May 2017
BAY-299 BRD1, TAF1, TAF1L Epigenetics Bromodomain 3
2.3333
1.0000
11 May 2017
GNE-2861 PAK4, PAK5, PAK6 Protein kinase STE20 3
2.6667
0.0000
30 May 2017
KI-696 KEAP1 Other post-translational modification Protein ubiquitination 3
3.3333
2.3333
01 Jun 2017
MI-888 MDM2 Other post-translational modification E3 ubiquitin ligase 3
3.0000
3.0000
06 Jun 2017
RO5353 MDM2 Other post-translational modification E3 ubiquitin ligase 2
4.0000
4.0000
06 Jun 2017
RO2468 MDM2 Other post-translational modification E3 ubiquitin ligase 2
3.0000
3.5000
06 Jun 2017
AMG232 MDM2 Other post-translational modification E3 ubiquitin ligase 3
4.0000
3.6667
06 Jun 2017
MI-77301 MDM2 Other post-translational modification E3 ubiquitin ligase 3
4.0000
4.0000
06 Jun 2017
RG7112 MDM2 Other post-translational modification E3 ubiquitin ligase 2
3.0000
3.5000
06 Jun 2017
AM-6761 MDM2 Other post-translational modification E3 ubiquitin ligase 3
4.0000
4.0000
06 Jun 2017
Pevonedistat NEDD8-activating enzyme Other post-translational modification Ubiquitin like modifier activating enzymes 3
3.0000
2.0000
06 Jun 2017
RG7388 MDM2 Other post-translational modification E3 ubiquitin ligase 3
3.6667
3.6667
06 Jun 2017
NMS-P118 PARP1 Other post-translational modification PARP 2
3.0000
3.5000
14 Jun 2017
KZR-504 PSMB9 Protein metabolism Proteasome subunit 3
3.6667
3.3333
21 Jun 2017
WEHI-539 BCLXL Other BCL2 family 2
3.5000
0.5000
22 Jun 2017
Cotransin SEC61 complex Integral membrane protein General secrectory pathway 3
2.3333
0.0000
23 Jun 2017
TTT20171 SDHC Other TCA cycle 2
1.0000
1.0000
27 Jun 2017
Linsitinib IGF1R, INSR, INSRR Protein kinase Tyrosine kinase 3
4.0000
4.0000
27 Jun 2017
Bistramide A Actin Structural protein Cytoskeleton 3
3.0000
0.3333
27 Jun 2017
CPI-1205 EZH2 Epigenetics Protein methyltransferase 2
2.5000
2.0000
06 Jul 2017
Eleutherobin Tubulin Structural protein Cytoskeleton 3
3.0000
0.0000
17 Jul 2017
T0901317 LXR-alpha, LXR-beta Hormone pathway Hormone receptor 2
4.0000
4.0000
18 Jul 2017
GW3965 LXR-alpha, LXR-beta Hormone pathway Hormone receptor 3
3.0000
3.6667
18 Jul 2017
Tubastatin A HDAC6, HDAC10 Epigenetics HDAC 2
3.0000
3.0000
20 Jul 2017
NI-57 BRPF1, BRD1, BRPF3 Epigenetics Bromodomain 3
3.0000
2.3333
25 Jul 2017
GSK2033 LXR-alpha, LXR-beta Hormone pathway Hormone receptor 0 27 Jul 2017
ICI-199441 OPRK1 GPCR Opioid receptors 3
3.0000
2.6667
09 Aug 2017
Glyburide ABCC8, KCNJ11 Ion channel Potassium channel 2
3.0000
3.5000
09 Aug 2017
Repaglinide ABCC8, KCNJ11 Ion channel Potassium channel 2
2.5000
3.0000
09 Aug 2017
T-26c MMP13 Protein metabolism Metallopeptidase 2
3.0000
2.0000
09 Aug 2017
(R)-9s ADRA1D GPCR Alpha-Adrenergic Receptor 3
3.6667
3.6667
31 Jan 2020
CM11 VHL Other E3 ubiquitin protein ligase 3
4.0000
0.0000
05 Mar 2020
AT1 BRD4 Epigenetics Bromodomain 2
4.0000
1.0000
05 Mar 2020
ABBV-744 BET BD2 Epigenetics Bromodomain 3
3.3333
3.3333
29 Apr 2020
Luminespib HSP90 Other post-translational modification Chaperone 3
4.0000
3.6667
11 May 2020
BAY-985 TBK1, IKBKE Protein kinase Ser/Thr Protein Kinase 2
3.0000
2.0000
16 May 2020
BAY-885 MAPK7 Protein kinase Ser/Thr Protein Kinase 3
2.6667
0.0000
17 May 2020
FS-694 MAPK14 Protein kinase CMGC Ser/Thr protein kinase 1
4.0000
0.0000
17 May 2020
MLi-2 LRRK2 Protein kinase Ser/Thr Protein Kinase 2
3.0000
2.5000
17 May 2020
A-485 EP300, CREBBP Epigenetics Bromodomain 3
3.3333
3.0000
20 May 2020
ABT-100 FNTB Epigenetics Transferase 1
3.0000
3.0000
21 May 2020
BI-1935 EPHX2 Other Epoxide Hydrolase 2 1
4.0000
4.0000
24 May 2020
BAY-707 NUDT1 Epigenetics Nudix Hydrolase 2
3.5000
2.0000
24 May 2020
BI-2545 ENPP2 Other Phosphodiesterase 3
3.6667
3.6667
24 May 2020
BTZO-1 MIF Other post-translational modification Tautomerase 2
4.0000
1.0000
25 May 2020
THPP-1 PDE10A Epigenetics Phosphodiesterase 2
3.5000
4.0000
26 May 2020
AC-4-130 STAT5B Transcription factor Signal transducer and transcription activator 3
2.3333
2.0000
27 May 2020
UCSF4226 MTNR1B GPCR Melatonin Receptor 3
3.6667
3.3333
29 May 2020
Ogerin GPR68 GPCR Proton Sensing GPCR 1
3.0000
3.0000
29 May 2020
UCSF7447 MTNR1A GPCR Melatonin Receptor 1
4.0000
3.0000
29 May 2020
(R)-Zinc-3573 MRGPRX2 GPCR Mast cell-specific receptor 2
1.5000
1.5000
29 May 2020
TP-024 GPR52 GPCR A orphan G protein-coupled receptor 0 29 May 2020
MRK-740 PRDM9 Epigenetics Histone methyltransferase 1
4.0000
0.0000
29 May 2020
SR-318 MAPK14 Protein kinase Activated Kinase 1
4.0000
2.0000
02 Jun 2020
SD-36 STAT3 Transcription factor Signal transducer and transcription activator 2
4.0000
4.0000
04 Jun 2020
BAY-549 ROCK1, ROCK2 Protein kinase Rho Associated Kinase 2
3.0000
3.0000
06 Jun 2020
MRTX849 KRAS Protein kinase GTPase 3
4.0000
4.0000
10 Jun 2020
AMG-510 KRAS Other G12C mutant 3
4.0000
4.0000
10 Jun 2020
ARS-1620 KRAS Protein kinase GTPase 0 11 Jun 2020
TH5427 NUDT5 Other Nudix Hydrolase 2
4.0000
0.0000
12 Jun 2020
BAY-826 TIE1, TEK, DDR1, DDR2 Protein kinase Tyrosine-protein Kinase 1
3.0000
3.0000
15 Jun 2020
DO264 ABHD12 Lipid metabolism Serine Esterase 2
3.5000
3.5000
16 Jun 2020
ULK-101 ULK1, ULK2 Protein kinase Autophagy Activating Kinases 2
3.5000
0.0000
17 Jun 2020
EML631 SPIN1 Transcription factor Chromatin regulator 0 17 Jun 2020
MLT-748 MALT1 Other Peptidase C14B 0 17 Jun 2020
25CN-NBOH 5-HT2A, 5-HT2c GPCR Serotonin Receptor 3
4.0000
3.6667
17 Jun 2020
TP-004 METAP2 Other Methionine Aminopeptidase 2
2.5000
2.5000
23 Jun 2020
CPI-1612 CREBBP, EP300 Epigenetics Histone Acetyl Transferase 3
3.3333
3.0000
23 Jun 2020
RUSKI-201 HHAT Other post-translational modification O-acyltransferase 3
2.6667
0.0000
07 Jul 2020
WM-1119 KAT6A Other Lysine Acetyltransferase 2
3.0000
3.0000
09 Jul 2020
M-808 Menin Epigenetics Scaffold Protein 3
2.3333
2.0000
09 Jul 2020
AB680 CD73 Other Membrane Protein 3
3.6667
3.6667
09 Jul 2020
AMG 176 MCL-1 Other Apoptosis Regulator 2
3.0000
2.5000
10 Jul 2020
LNP-023 CFB Other Serine Protease 0 10 Jul 2020
MCC950 NLRP3 Other NACHT, LRR and PYD domains-containing Protein 1
3.0000
3.0000
10 Jul 2020
SR9238 LXR-alpha, LXR-beta Hormone pathway Hormone Receptor 0 16 Jul 2020
LXR-623 LXR-alpha, LXR-beta Hormone pathway Hormone Receptor 2
2.5000
2.0000
16 Jul 2020
CMLD-2 ELAVL1 Other RNA Binding Protein 2
2.0000
0.0000
16 Jul 2020
BAY-1816032 BUB1 Protein kinase Ser/Thr Protein Kinase 2
4.0000
4.0000
20 Jul 2020
PT2399 HIF-2α Transcription factor Hypoxia-Inducible Factor 1
4.0000
4.0000
28 Jul 2020
BAY-3827 PRKAA1, RPS6KA1 Protein kinase Ser/Thr Protein Kinase 1
4.0000
0.0000
03 Aug 2020
BAY1125976 AKT1, AKT2 Protein kinase Ser/Thr Protein Kinase 3
3.6667
3.6667
10 Aug 2020
PT2385 HIF-2α Transcription factor Hypoxia-Inducible Factor 0 23 Sep 2020
TP-020 MGAT2 Other post-translational modification N-acetylglucosaminyltransferase 1
2.0000
3.0000
24 Sep 2020
XMD8-87 ACK1 Protein kinase Tyrosine Kinase 1
3.0000
0.0000
13 Oct 2020
THZ531 CDK12, CDK13 Protein kinase cyclin-dependent serine/threonine kinase 1
4.0000
0.0000
14 Oct 2020
XMD-12 Aurora A/B/C Protein kinase cell cycle-regulated kinase 1
4.0000
2.0000
14 Oct 2020
PF-06869206 NaPi2A Ion channel type II sodium-phosphate cotransporter 0 20 Oct 2020
GSK2194069 FASN Lipid metabolism Synthase 0 21 Oct 2020
GSK2982772 RIPK1 Protein kinase Ser/Thr Protein Kinase 0 21 Oct 2020
MBM-55 NEK2 Protein kinase Ser/Thr Protein Kinase 0 22 Oct 2020
QC6352 KDM4C Epigenetics Protein Demethylase 0 22 Oct 2020
LSN 3213128 ATIC Other post-translational modification formyltransferase and cyclohydrolase 0 22 Oct 2020
NCT-505 ALDH1A1 Other aldehyde dehydrogenase 0 22 Oct 2020
SB-612111 OPRL1 GPCR Opioid Receptor 0 23 Oct 2020
GSK2973980A DGAT1 Other Diacylglycerol O-acyltransferase 0 23 Oct 2020
AZD3988 DGAT1 Other Diacylglycerol O-acyltransferase 0 23 Oct 2020
AZD-6482 PIK3CB Protein kinase phosphoinositide-3-kinase 1
3.0000
3.0000
26 Oct 2020
Capmatinib MET Protein kinase receptor tyrosine kinase 0 26 Oct 2020
Adavosertib WEE1 Protein kinase Ser/Thr Protein Kinase 0 26 Oct 2020
NIK SMI1 MAP3K14 Protein kinase Ser/Thr Protein Kinase 0 27 Oct 2020
Relacatib CTSK, CTSL, CTSV Protein metabolism Protease 1
3.0000
3.0000
27 Oct 2020
RU.521 CGAS Other cyclic GMP-AMP synthase 0 05 Nov 2020
BSJ-03-123 CDK6 Protein kinase Ser/Thr Protein Kinase 0 12 Nov 2020
VZ185 BRD7, BRD9 Epigenetics Bromodomain 0 12 Nov 2020
TBK1 PROTAC 3i TBK1 Protein kinase Ser/Thr Protein Kinase 0 12 Nov 2020
THAL-SNS-032 CDK9, CDK10 Protein kinase cyclin dependent kinase 0 12 Nov 2020
TL13-112 ALK Protein kinase receptor tyrosine kinase 0 12 Nov 2020
dTRIM24 TRIM24 Transcription factor tripartite motif family 0 13 Nov 2020
dTAG-13 FKBP1A (F36V mutant) Other Prolyl Isomerase 0 14 Nov 2020
TH1760 NUDT15 Epigenetics Nudix Hydrolase 0 16 Nov 2020
GNF-5837 TRKA, TRKB, TRKC Protein kinase Tyrosine kinase 0 17 Nov 2020
TAK-243 UBA1 Other post-translational modification Ubiquitin-conjugating enzyme 0 17 Nov 2020
GDC-0834 BTK Protein kinase Tyrosine kinase 0 17 Nov 2020
Asciminib BCR-ABL Protein kinase Tyrosine kinase 0 23 Nov 2020
dBET6 BET Bromodomains Epigenetics Bromodomain 0 23 Nov 2020
MG-277 GSPT1 Other Translation Termination Factor 0 24 Nov 2020
MD-224 MDM2 Other E3 ubiquitin ligase 0 24 Nov 2020
MZP-54 BRD2, BRD3, BRD4 Epigenetics Bromodomain 0 25 Nov 2020
GNE-049 CREBBP/EP300 Epigenetics Bromodomain 0 25 Nov 2020
GNE-781 CREBBP/EP300 Epigenetics Bromodomain 0 25 Nov 2020
WZ4002 EGFR Protein kinase Tyrosine kinase 0 25 Nov 2020
A-770041 LCK Protein kinase Tyrosine kinase 0 25 Nov 2020
MK-8033 MET, MST1R Protein kinase Tyrosine kinase 0 26 Nov 2020
AMG 337 MET Protein kinase Tyrosine kinase 0 26 Nov 2020
U18666A NPC1 Other Intracellular Cholesterol Transporter 0 26 Nov 2020
AC710 PDGFRα, PDGFRβ, KIT, FLT3, CSF1R Protein kinase Tyrosine kinase 0 27 Nov 2020
G749 FLT3 Protein kinase Tyrosine kinase 0 27 Nov 2020
AZ-960 JAK2 Protein kinase Tyrosine kinase 0 27 Nov 2020