Browse Probes

Probe Name Protein target Target class Subclass Number of SAB Reviews Avg Rating (In Cell)sort ascending Avg Rating (In Vivo) Published on
UNC0642 EHMT2, EHMT1 Epigenetics Protein methyltransferase 3
4.0000
2.6667
08 Aug 2016
T0901317 LXR-alpha, LXR-beta Hormone pathway Hormone receptor 2
4.0000
4.0000
18 Jul 2017
GSK2334470 PDK1 Protein kinase AGC 3
4.0000
2.6667
10 Dec 2015
BI-1935 EPHX2 Other Epoxide Hydrolase 2 1
4.0000
4.0000
24 May 2020
BAY-3827 PRKAA1, RPS6KA1 Protein kinase Ser/Thr Protein Kinase 1
4.0000
0.0000
03 Aug 2020
CM11 VHL Other E3 ubiquitin protein ligase 3
4.0000
0.0000
05 Mar 2020
GSK343 EZH2 Epigenetics Protein methyltransferase 3
4.0000
0.0000
02 Oct 2015
BYL-719 PIK3CA Lipid kinase Class I 3
4.0000
4.0000
10 Dec 2015
SD-36 STAT3 Transcription factor Signal transducer and transcription activator 2
4.0000
4.0000
04 Jun 2020
XMD-12 Aurora A/B/C Protein kinase cell cycle-regulated kinase 1
4.0000
2.0000
14 Oct 2020
MK-5108 AURKA Protein kinase Other 3
4.0000
4.0000
10 Dec 2015
AX15836 MAPK7 Protein kinase CMGC 3
4.0000
0.6667
05 Dec 2016
PD0332991 CDK4, CDK6 Protein kinase CMGC 3
4.0000
3.0000
10 Dec 2015
TH5427 NUDT5 Other Nudix Hydrolase 2
4.0000
0.0000
12 Jun 2020
AMG232 MDM2 Other post-translational modification E3 ubiquitin ligase 3
4.0000
3.6667
06 Jun 2017
CPI-360 EZH2 Epigenetics Protein methyltransferase 3
4.0000
2.3333
08 Aug 2016
25CN-NBOH 5-HT2A, 5-HT2c GPCR Serotonin Receptor 3
4.0000
3.6667
17 Jun 2020
EPZ015666 PRMT5 Epigenetics Protein methyltransferase 3
4.0000
4.0000
25 Jan 2016
OICR-9429 WDR5 Structural protein WD40-repeat proteins 3
4.0000
0.6667
02 Oct 2015
(R)-PFI-2 SETD7 Epigenetics Protein methyltransferase 3
4.0000
0.0000
02 Oct 2015
Venetoclax BCL2 Other Protein Phosphatase 3
4.0000
4.0000
07 Mar 2017
CGI1746 BTK Protein kinase Tyrosine kinase 3
4.0000
4.0000
10 Dec 2015
MRK-740 PRDM9 Epigenetics Histone methyltransferase 1
4.0000
0.0000
29 May 2020
RO5353 MDM2 Other post-translational modification E3 ubiquitin ligase 2
4.0000
4.0000
06 Jun 2017
EPZ004777 DOT1L Epigenetics Protein Methyltransferase 3
4.0000
0.3333
08 Aug 2016
Luminespib HSP90 Other post-translational modification Chaperone 3
4.0000
3.6667
11 May 2020
Ruxolitinib JAK1, JAK2 Protein kinase Tyrosine Kinase 3
4.0000
4.0000
10 Dec 2015
PT2399 HIF-2α Transcription factor Hypoxia-Inducible Factor 1
4.0000
4.0000
28 Jul 2020
CP-724714 ERBB2 Protein kinase Tyrosine kinase 3
4.0000
4.0000
10 Dec 2015
S63845 MCL1 Other BCL2 family 2
4.0000
3.0000
24 Apr 2017
MT1 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 3
4.0000
4.0000
04 Nov 2016
THZ531 CDK12, CDK13 Protein kinase cyclin-dependent serine/threonine kinase 1
4.0000
0.0000
14 Oct 2020
SCH772984 MAPK1, MAPK3 Protein kinase CMGC 3
4.0000
3.3333
10 Dec 2015
MS023 PRMT1, PRMT3, PRMT4, PRMT6, PRMT8 Epigenetics Protein methyltransferase 3
4.0000
0.0000
05 Nov 2015
MI-77301 MDM2 Other post-translational modification E3 ubiquitin ligase 3
4.0000
4.0000
06 Jun 2017
Linsitinib IGF1R, INSR, INSRR Protein kinase Tyrosine kinase 3
4.0000
4.0000
27 Jun 2017
FS-694 MAPK14 Protein kinase CMGC Ser/Thr protein kinase 1
4.0000
0.0000
17 May 2020
CPI-0610 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 3
4.0000
4.0000
24 Apr 2017
UNC1215 L3MBTL3 Epigenetics Malignant brain tumor Reader 3
4.0000
1.0000
02 Oct 2015
BTZO-1 MIF Other post-translational modification Tautomerase 2
4.0000
1.0000
25 May 2020
GSK481 RIPK1 Protein kinase Ser/Thr Protein Kinase 3
4.0000
0.0000
16 Feb 2017
Niraparib PARP1, PARP2 Other post-translational modification PARP 3
4.0000
3.6667
29 Jul 2016
A-196 KMT5B, KMT5C Epigenetics Protein methyltransferase 3
4.0000
1.0000
09 Nov 2015
CCT251236 PIR Other Cupin 2
4.0000
3.0000
17 Jan 2017
JQ1 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 3
4.0000
3.0000
13 Jul 2015
BAY-1816032 BUB1 Protein kinase Ser/Thr Protein Kinase 2
4.0000
4.0000
20 Jul 2020
CH5424802 ALK Protein kinase Tyrosine kinase 3
4.0000
4.0000
10 Dec 2015
BAY-598 SMYD2 Epigenetics Protein methyltransferase 3
4.0000
4.0000
09 Nov 2015
SR-318 MAPK14 Protein kinase Activated Kinase 1
4.0000
2.0000
02 Jun 2020
FM-381 JAK3 Protein kinase Tyrosine kinase 3
4.0000
0.0000
24 Apr 2017
VX-745 MAPK14 Protein kinase CMGC 3
4.0000
3.6667
10 Dec 2015
MRTX849 KRAS Protein kinase GTPase 3
4.0000
4.0000
10 Jun 2020
PFI-1 BRD2, BRD3, BRD4, BRDT Epigenetics Bromodomain 3
4.0000
2.6667
16 Jul 2015
AT1 BRD4 Epigenetics Bromodomain 2
4.0000
1.0000
05 Mar 2020
A-366 EHMT2, EHMT1 Epigenetics Protein methyltransferase 3
4.0000
1.6667
02 Oct 2015
CCT251545 CDK8, CDK19 Protein kinase CMGC 3
4.0000
3.3333
13 Jan 2017
AM-6761 MDM2 Other post-translational modification E3 ubiquitin ligase 3
4.0000
4.0000
06 Jun 2017
CPI-169 EZH1, EZH2 Epigenetics Protein methyltransferase 3
4.0000
2.3333
08 Aug 2016
UCSF7447 MTNR1A GPCR Melatonin Receptor 1
4.0000
3.0000
29 May 2020
PFI-3 SMARCA2, SMARCA4, PBRM1 Epigenetics Bromodomain 2
4.0000
1.0000
07 Mar 2017
Veliparib PARP1, PARP2 Other post-translational modification PARP 3
4.0000
2.6667
29 Jul 2016
AMG-510 KRAS Other G12C mutant 3
4.0000
4.0000
10 Jun 2020
GSK4027 PCAF, GCN5 Epigenetics Bromodomain 5
3.8000
1.4000
13 Mar 2017
SGC707 PRMT3 Epigenetics Protein methyltransferase 4
3.7500
2.0000
02 Oct 2015
SGC0946 DOT1L Epigenetics Protein methyltransferase 4
3.7500
0.0000
02 Oct 2015
EED226 EED Epigenetics Polycomb family 4
3.7500
2.7500
30 Mar 2017
P505-15 SYK Protein kinase Tyrosine Kinase 3
3.6667
3.6667
10 Dec 2015
AMG900 AURKA, AURKB, AURKC Protein kinase Other 3
3.6667
3.6667
10 Dec 2015
AZD2014 MTOR Protein kinase Atypical 3
3.6667
4.0000
10 Dec 2015
GSK484 PADI4 Epigenetics Arginine deaminase 3
3.6667
1.3333
09 Nov 2015
PF-CBP1 CREBBP Epigenetics Bromodomain 3
3.6667
0.0000
13 Mar 2017
BLU9931 FGFR4 Protein kinase Tyrosine kinase 3
3.6667
2.6667
14 Mar 2017
CHIR-99021 GSK3A, GSK3B Protein kinase CMGC 3
3.6667
2.6667
16 Jul 2015
Skepinone-L MAPK14 Protein kinase CMGC Ser/Thr protein kinase 3
3.6667
3.0000
15 Mar 2017
NVS-PAK1-1 PAK1 Protein kinase STE 3
3.6667
1.3333
29 Nov 2016
EI1 EZH2 Epigenetics Protein methyltransferase 3
3.6667
1.3333
08 Aug 2016
AZD1152 AURKB Protein kinase Other 3
3.6667
3.6667
10 Dec 2015
SGX-523 MET Protein kinase Tyrosine Kinase 3
3.6667
3.6667
10 Dec 2015
(R)-9s ADRA1D GPCR Alpha-Adrenergic Receptor 3
3.6667
3.6667
31 Jan 2020
CCT241533 CHEK2 Protein kinase CAMK 3
3.6667
0.6667
10 Dec 2015
VH298 VHL Other post-translational modification E3 ubiquitin ligase 3
3.6667
0.0000
15 Nov 2016
PF-477736 CHEK1 Protein kinase CAMK 3
3.6667
3.6667
10 Dec 2015
KZR-504 PSMB9 Protein metabolism Proteasome subunit 3
3.6667
3.3333
21 Jun 2017
BMS-911543 JAK2 Protein kinase Tyrosine kinase 3
3.6667
3.6667
29 Jul 2016
UCSF4226 MTNR1B GPCR Melatonin Receptor 3
3.6667
3.3333
29 May 2020
EPZ-5676 DOT1L Epigenetics Protein methyltransferase 3
3.6667
3.3333
02 Oct 2015
RG7388 MDM2 Other post-translational modification E3 ubiquitin ligase 3
3.6667
3.6667
06 Jun 2017
G-5555 PAK1, PAK2, PAK3 Protein kinase STE 3
3.6667
2.6667
29 Nov 2016
A-395 EED Epigenetics Polycomb family 3
3.6667
2.0000
31 Jan 2017
AB680 CD73 Other Membrane Protein 3
3.6667
3.6667
09 Jul 2020
GNF-5 BCR-ABL Protein kinase Tyrosine kinase 3
3.6667
3.3333
10 Dec 2015
BI-2545 ENPP2 Other Phosphodiesterase 3
3.6667
3.6667
24 May 2020
BAY1125976 AKT1, AKT2 Protein kinase Ser/Thr Protein Kinase 3
3.6667
3.6667
10 Aug 2020
GSK583 RIPK2 Protein kinase AGC 3
3.6667
3.3333
09 Mar 2017
EPZ011989 EZH1, EZH2 Epigenetics Protein methyltransferase 3
3.6667
2.6667
02 Oct 2015
BGJ-398 FGFR1, FGFR2, FGFR3, FGFR4 Protein kinase Tyrosine Kinase 3
3.6667
3.3333
10 Dec 2015
Tofacitinib JAK1, JAK2, JAK3 Protein kinase Tyrosine Kinase 3
3.6667
2.3333
10 Dec 2015
Romidepsin HDAC1, HDAC2, HDAC3, HDAC8 Epigenetics HDAC 3
3.6667
3.0000
11 Apr 2017
GDC-0879 BRAF V600E Protein kinase TKL 3
3.6667
1.6667
10 Dec 2015
ULK-101 ULK1, ULK2 Protein kinase Autophagy Activating Kinases 2
3.5000
0.0000
17 Jun 2020
THPP-1 PDE10A Epigenetics Phosphodiesterase 2
3.5000
4.0000
26 May 2020
MZ1 BRD4 Epigenetics Bromodomain 4
3.5000
0.0000
18 Nov 2016
DO264 ABHD12 Lipid metabolism Serine Esterase 2
3.5000
3.5000
16 Jun 2020
BAY-707 NUDT1 Epigenetics Nudix Hydrolase 2
3.5000
2.0000
24 May 2020
UNC1999 EZH1, EZH2 Epigenetics Protein methyltransferase 2
3.5000
1.0000
02 Oct 2015
WEHI-539 BCLXL Other BCL2 family 2
3.5000
0.5000
22 Jun 2017
GSK-J4 KDM6A, KDM6B Epigenetics Lysine demethylase 3
3.3333
1.0000
04 Nov 2015
EPZ-6438 EZH2 Epigenetics Protein Methyltransferase 3
3.3333
2.3333
08 Aug 2016
CCT244747 CHEK1 Protein kinase CAMK 3
3.3333
3.0000
09 Sep 2016
PF3644022 MAPKAPK2 Protein kinase CAMK 3
3.3333
2.3333
10 Dec 2015
CPI-1612 CREBBP, EP300 Epigenetics Histone Acetyl Transferase 3
3.3333
3.0000
23 Jun 2020
KI-696 KEAP1 Other post-translational modification Protein ubiquitination 3
3.3333
2.3333
01 Jun 2017
SGC-CBP30 CREBBP, EP300 Epigenetics Bromodomain 3
3.3333
0.0000
03 Nov 2015
Selumetinib MAP2K1 Protein kinase STE 3
3.3333
3.0000
10 Dec 2015
GSK591 PRMT5 Epigenetics Protein methyltransferase 3
3.3333
1.3333
25 Jan 2016
Rapamycin MTOR Protein kinase Atypical 3
3.3333
3.0000
10 Dec 2015
Tubacin HDAC6 Epigenetics HDAC 3
3.3333
2.0000
10 Apr 2017
ML323 USP1, WDR48 Other post-translational modification Deubiquitinase 3
3.3333
0.0000
14 Oct 2016
AC220 FLT3 Protein kinase Tyrosine Kinase 3
3.3333
2.6667
10 Dec 2015
Talazoparib PARPs Other post-translational modification PARP 3
3.3333
3.6667
29 Jul 2016
PDD00017273 PARG DNA replication & repair enzyme Glycohydrolase 3
3.3333
0.3333
18 Oct 2016
ABBV-744 BET BD2 Epigenetics Bromodomain 3
3.3333
3.3333
29 Apr 2020
NVP-AEW541 IGF1R Protein kinase Tyrosine Kinase 3
3.3333
3.0000
10 Dec 2015
AMG-18 ERN1 Protein kinase Other 3
3.3333
2.0000
08 Dec 2016
THZ1 CDK7 Protein kinase CMGC 3
3.3333
3.0000
10 Dec 2015
A-485 EP300, CREBBP Epigenetics Bromodomain 3
3.3333
3.0000
20 May 2020
Filgotinib JAK1 Protein kinase Tyrosine kinase 3
3.3333
3.6667
10 Feb 2017
JNK-IN-8 MAPK8, MAPK9, MAPK10 Protein kinase CMGC 3
3.3333
0.6667
10 Dec 2015
BiBET BRD4, BRD3, BRD2, BRDT Epigenetics Bromodomain 3
3.3333
0.6667
12 Dec 2016
MI-888 MDM2 Other post-translational modification E3 ubiquitin ligase 3
3.0000
3.0000
06 Jun 2017
GSK864 IDH1 (mutant) Other Dehydrogenase 2
3.0000
2.5000
10 Nov 2015
I-CBP112 CREBBP, EP300 Epigenetics Bromodomain 3
3.0000
2.0000
03 Nov 2015
BAY-985 TBK1, IKBKE Protein kinase Ser/Thr Protein Kinase 2
3.0000
2.0000
16 May 2020
MCC950 NLRP3 Other NACHT, LRR and PYD domains-containing Protein 1
3.0000
3.0000
10 Jul 2020
eCF506 SRC Protein kinase Tyrosine kinase 4
3.0000
2.2500
23 Feb 2017
Salvinorin A OPRK1 GPCR Opioid receptor 3
3.0000
3.0000
16 Jul 2015
AZD-6482 PIK3CB Protein kinase phosphoinositide-3-kinase 1
3.0000
3.0000
26 Oct 2020
RGFP966 HDAC3 Epigenetics HDAC 3
3.0000
3.0000
10 Apr 2017
UNC2025 MERTK, FLT3 Protein kinase Tyrosine kinase 3
3.0000
3.0000
06 Apr 2017
Eleutherobin Tubulin Structural protein Cytoskeleton 3
3.0000
0.0000
17 Jul 2017
BIX-02188 MAP2K5 Protein kinase STE 3
3.0000
1.3333
10 Dec 2015
Ogerin GPR68 GPCR Proton Sensing GPCR 1
3.0000
3.0000
29 May 2020
MLi-2 LRRK2 Protein kinase Ser/Thr Protein Kinase 2
3.0000
2.5000
17 May 2020
ICI-199441 OPRK1 GPCR Opioid receptors 3
3.0000
2.6667
09 Aug 2017
Olaparib PARPs Other post-translational modification PARP 3
3.0000
3.0000
29 Jul 2016
WZ4003 NUAK1, NUAK2 Protein kinase CAMK 3
3.0000
0.6667
10 Dec 2015
KH-CB19 CLK1, CLK4, DYRK1A Protein kinase CMGC 3
3.0000
0.6667
10 Dec 2015
Tubastatin A HDAC6, HDAC10 Epigenetics HDAC 2
3.0000
3.0000
20 Jul 2017
eCF309 MTOR Protein kinase Atypical 3
3.0000
0.0000
17 Oct 2016
E7449 PARP1, PARP2, TNKS, TNKS2 Other post-translational modification PARP 3
3.0000
3.0000
29 Jul 2016
AZ191 DYRK1B Protein kinase CMGC 3
3.0000
0.0000
10 Dec 2015
A-1155463 BCLXL Other BCL2 family 3
3.0000
2.6667
04 Apr 2017
AMG 176 MCL-1 Other Apoptosis Regulator 2
3.0000
2.5000
10 Jul 2020
RO2468 MDM2 Other post-translational modification E3 ubiquitin ligase 2
3.0000
3.5000
06 Jun 2017
NI-57 BRPF1, BRD1, BRPF3 Epigenetics Bromodomain 3
3.0000
2.3333
25 Jul 2017
BAY-826 TIE1, TEK, DDR1, DDR2 Protein kinase Tyrosine-protein Kinase 1
3.0000
3.0000
15 Jun 2020
ABT-100 FNTB Epigenetics Transferase 1
3.0000
3.0000
21 May 2020
HG-9-91-01 SIK1, SIK2, SIK3 Protein kinase CAMK 3
3.0000
1.6667
10 Dec 2015
XMD8-87 ACK1 Protein kinase Tyrosine Kinase 1
3.0000
0.0000
13 Oct 2020
T-26c MMP13 Protein metabolism Metallopeptidase 2
3.0000
2.0000
09 Aug 2017
NMS-P118 PARP1 Other post-translational modification PARP 2
3.0000
3.5000
14 Jun 2017
GW3965 LXR-alpha, LXR-beta Hormone pathway Hormone receptor 3
3.0000
3.6667
18 Jul 2017
AZ6102 TNKS, TNKS2 Other post-translational modification PARP 3
3.0000
2.0000
29 Jul 2016
GNE7915 LRRK2 Protein kinase TKL 3
3.0000
3.0000
10 Dec 2015
ACY-738 HDAC6 Epigenetics HDAC 3
3.0000
2.6667
10 Apr 2017
Pevonedistat NEDD8-activating enzyme Other post-translational modification Ubiquitin like modifier activating enzymes 3
3.0000
2.0000
06 Jun 2017
BAY-549 ROCK1, ROCK2 Protein kinase Rho Associated Kinase 2
3.0000
3.0000
06 Jun 2020
BMX-IN-1 BMX Protein kinase Tyrosine kinase 3
3.0000
0.0000
10 Dec 2015
BAZ2-ICR BAZ2A, BAZ2B Epigenetics Bromodomain 3
3.0000
1.3333
29 Jul 2016
WM-1119 KAT6A Other Lysine Acetyltransferase 2
3.0000
3.0000
09 Jul 2020
BI-9564 BRD9, BRD7 Epigenetics Bromodomain 3
3.0000
3.0000
29 Jul 2016
PF-3758309 PAK1, PAK4, PAK5, PAK6 Protein kinase STE 3
3.0000
3.0000
10 Dec 2015
Glyburide ABCC8, KCNJ11 Ion channel Potassium channel 2
3.0000
3.5000
09 Aug 2017
Relacatib CTSK, CTSL, CTSV Protein metabolism Protease 1
3.0000
3.0000
27 Oct 2020
Bistramide A Actin Structural protein Cytoskeleton 3
3.0000
0.3333
27 Jun 2017
I-BRD9 BRD9 Epigenetics Bromodomain 3
3.0000
0.0000
29 Jul 2016
RG7112 MDM2 Other post-translational modification E3 ubiquitin ligase 2
3.0000
3.5000
06 Jun 2017
Pictilisib PIK3CA, PIK3CD Lipid kinase Class I 4
2.7500
2.5000
10 Dec 2015
Bafetinib BCR-ABL, LYN Protein kinase Tyrosine Kinase 4
2.7500
2.5000
10 Dec 2015
AVL-292 BTK Protein kinase Tyrosine kinase 3
2.6667
2.3333
10 Dec 2015
A-1210477 MCL1 Other BCL2 family 3
2.6667
1.0000
04 Apr 2017
UNC3866 CBX7, CBX4 Epigenetics Methyl-lysine reader 3
2.6667
0.0000
09 Sep 2016
XMD8-92 MAPK7 Protein kinase CMGC 3
2.6667
1.0000
10 Dec 2015
MPS1-IN-1 MPS1 Protein kinase Other 3
2.6667
0.6667
10 Dec 2015
RUSKI-201 HHAT Other post-translational modification O-acyltransferase 3
2.6667
0.0000
07 Jul 2020
STO609 CAMKK1, CAMKK2 Protein kinase Other 3
2.6667
0.0000
10 Dec 2015
AZ0108 PARP1, PARP2, PARP6 Other post-translational modification PARP 3
2.6667
2.0000
29 Jul 2016
I-BET151 BRD2, BRD3, BRD4 Epigenetics Bromodomain 3
2.6667
2.6667
16 Jul 2015
GNE-2861 PAK4, PAK5, PAK6 Protein kinase STE20 3
2.6667
0.0000
30 May 2017
DDR1-IN-1 DDR1 Protein kinase Tyrosine Kinase 3
2.6667
0.6667
10 Dec 2015
EPZ020411 PRMT6 Epigenetics Protein methyltransferase 3
2.6667
2.6667
05 Nov 2015
BAY-885 MAPK7 Protein kinase Ser/Thr Protein Kinase 3
2.6667
0.0000
17 May 2020
2-MT 63 TEK Protein kinase Tyrosine kinase 3
2.6667
2.6667
13 Mar 2017
Afatinib EGFR, ERBB2 Protein kinase Tyrosine Kinase 3
2.6667
2.6667
10 Dec 2015
VE-821 ATR Protein kinase Atypical 3
2.6667
0.0000
10 Dec 2015
CPI-1205 EZH2 Epigenetics Protein methyltransferase 2
2.5000
2.0000
06 Jul 2017
TP-004 METAP2 Other Methionine Aminopeptidase 2
2.5000
2.5000
23 Jun 2020
Repaglinide ABCC8, KCNJ11 Ion channel Potassium channel 2
2.5000
3.0000
09 Aug 2017
L-Moses PCAF, GCN5 Epigenetics Bromodomain 6
2.5000
0.3333
13 Mar 2017
LXR-623 LXR-alpha, LXR-beta Hormone pathway Hormone Receptor 2
2.5000
2.0000
16 Jul 2020
GSK-5959 BRPF1 Epigenetics Bromodomain 3
2.3333
0.0000
04 Apr 2017
UNC0638 EHMT2, EHMT1 Epigenetics Protein methyltransferase 3
2.3333
1.0000
02 Oct 2015
GSK2801 BAZ2A, BAZ2B Epigenetics Bromodomain 3
2.3333
1.3333
29 Jul 2016
CPI-637 CREBBP, EP300 Epigenetics Bromodomain 3
2.3333
0.0000
25 Apr 2017
GPR40ant39 FFAR1 GPCR Free fatty acid receptors 3
2.3333
2.0000
10 May 2017
JAK3i JAK3 Protein kinase Tyrosine kinase 3
2.3333
2.3333
09 Sep 2016
CX-4945 CSNK2A1 Protein kinase CMGC 3
2.3333
2.0000
10 Dec 2015
M-808 Menin Epigenetics Scaffold Protein 3
2.3333
2.0000
09 Jul 2020
RSL3 GPX4 Lipid metabolism Glutathione Peroxidase 3
2.3333
2.0000
14 Oct 2016
MIV-6R KMT2A Epigenetics Protein methyltransferase 3
2.3333
0.6667
08 Aug 2016
CP-673451 PDGFRbeta Protein kinase Tyrosine kinase 3
2.3333
1.6667
10 Dec 2015
BAY-299 BRD1, TAF1, TAF1L Epigenetics Bromodomain 3
2.3333
1.0000
11 May 2017
Cotransin SEC61 complex Integral membrane protein General secrectory pathway 3
2.3333
0.0000
23 Jun 2017
AC-4-130 STAT5B Transcription factor Signal transducer and transcription activator 3
2.3333
2.0000
27 May 2020
ABPA3 UBA1, UBA3 Other post-translational modification E1 enzyme 3
2.0000
1.3333
29 Jul 2016
PF-4800567 CSNK1E Protein kinase CK1 3
2.0000
0.6667
10 Dec 2015
Englerin A TRPC4, TRPC5 Ion channel Transient receptor potential channels 3
2.0000
0.3333
31 Jan 2017
TP-020 MGAT2 Other post-translational modification N-acetylglucosaminyltransferase 1
2.0000
3.0000
24 Sep 2020
LP99 BRD7, BRD9 Epigenetics Bromodomain 3
2.0000
0.0000
29 Jul 2016
JQEZ5 EZH2 Epigenetics Protein methyltransferase 3
2.0000
2.3333
29 Jul 2016
BI2536 PLK1, PLK2, PLK3 Protein kinase Other 3
2.0000
2.0000
10 Dec 2015
KU-60019 ATM Protein kinase Atypical 3
2.0000
1.6667
10 Dec 2015
DS-437 PRMT5, PRMT7 Epigenetics Protein methyltransferase 3
2.0000
0.3333
08 Aug 2016
AGI-6780 IDH2 (R140Q mutant) Other Dehydrogenase 3
2.0000
0.3333
14 Mar 2017
BMS-265246 CDK, CDK2 Protein kinase CMGC 3
2.0000
0.6667
10 Dec 2015
BI-D1870 RPS6KA1, RPS6KA2, RPS6KA3, RPS6KA6 Protein kinase AGC 3
2.0000
0.3333
10 Dec 2015
AGI-5198 IDH1 (R132H mutant) Other Dehydrogenase 3
2.0000
1.6667
10 Nov 2015
CMLD-2 ELAVL1 Other RNA Binding Protein 2
2.0000
0.0000
16 Jul 2020
LLY-507 SMYD2 Epigenetics Protein methyltransferase 3
2.0000
0.0000
02 Oct 2015
WH-4-023 LCK, SRC Protein kinase Tyrosine Kinase 5
1.8000
0.8000
10 Dec 2015
NI-42 BRPF1, BRD1, BRPF3 Epigenetics Bromodomain 3
1.6667
1.6667
30 Jan 2017
BIX-01294 EHMT2 Epigenetics Protein methyltransferase 3
1.6667
1.0000
08 Aug 2016
TX1-85-1 ERBB3 Protein kinase Tyrosine kinase 3
1.6667
0.0000
10 Dec 2015
CFI-400945 PLK4 Protein kinase Other 3
1.6667
1.6667
10 Dec 2015
Cortistatin A CDK8, CDK19 Protein kinase CMGC 3
1.6667
1.0000
09 Sep 2016
(R)-Zinc-3573 MRGPRX2 GPCR Mast cell-specific receptor 2
1.5000
1.5000
29 May 2020
URMC-099 MLK1, MLK2, MLK3 Protein kinase TKL 3
1.3333
1.3333
10 Dec 2015
XAV939 TNKS, TNKS2, PARP1, PARP2 Other post-translational modification PARP 3
1.3333
0.0000
29 Jul 2016
JW55 TNKS, TNKS2 Other post-translational modification PARP 3
1.0000
0.3333
29 Jul 2016
TTT20171 SDHC Other TCA cycle 2
1.0000
1.0000
27 Jun 2017
Imatinib BCR-ABL, PDGFR, KIT Protein kinase Tyrosine kinase 3
1.0000
1.0000
10 Dec 2015
MZP-54 BRD2, BRD3, BRD4 Epigenetics Bromodomain 0 25 Nov 2020
MBM-55 NEK2 Protein kinase Ser/Thr Protein Kinase 0 22 Oct 2020
TBK1 PROTAC 3i TBK1 Protein kinase Ser/Thr Protein Kinase 0 12 Nov 2020
GNE-049 CREBBP/EP300 Epigenetics Bromodomain 0 25 Nov 2020
AC710 PDGFRα, PDGFRβ, KIT, FLT3, CSF1R Protein kinase Tyrosine kinase 0 27 Nov 2020
NCT-505 ALDH1A1 Other aldehyde dehydrogenase 0 22 Oct 2020
SR9238 LXR-alpha, LXR-beta Hormone pathway Hormone Receptor 0 16 Jul 2020
WZ4002 EGFR Protein kinase Tyrosine kinase 0 25 Nov 2020
NIK SMI1 MAP3K14 Protein kinase Ser/Thr Protein Kinase 0 27 Oct 2020
U18666A NPC1 Other Intracellular Cholesterol Transporter 0 26 Nov 2020
TL13-112 ALK Protein kinase receptor tyrosine kinase 0 12 Nov 2020
MD-224 MDM2 Other E3 ubiquitin ligase 0 24 Nov 2020
LNP-023 CFB Other Serine Protease 0 10 Jul 2020
GSK2982772 RIPK1 Protein kinase Ser/Thr Protein Kinase 0 21 Oct 2020
AZD3988 DGAT1 Other Diacylglycerol O-acyltransferase 0 23 Oct 2020
MK-8033 MET, MST1R Protein kinase Tyrosine kinase 0 26 Nov 2020
RU.521 CGAS Other cyclic GMP-AMP synthase 0 05 Nov 2020
dBET6 BET Bromodomains Epigenetics Bromodomain 0 23 Nov 2020
ARS-1620 KRAS Protein kinase GTPase 0 11 Jun 2020
MLT-748 MALT1 Other Peptidase C14B 0 17 Jun 2020
A-770041 LCK Protein kinase Tyrosine kinase 0 25 Nov 2020
LSN 3213128 ATIC Other post-translational modification formyltransferase and cyclohydrolase 0 22 Oct 2020
GSK2033 LXR-alpha, LXR-beta Hormone pathway Hormone receptor 0 27 Jul 2017
GDC-0834 BTK Protein kinase Tyrosine kinase 0 17 Nov 2020
Adavosertib WEE1 Protein kinase Ser/Thr Protein Kinase 0 26 Oct 2020
PT2385 HIF-2α Transcription factor Hypoxia-Inducible Factor 0 23 Sep 2020
VZ185 BRD7, BRD9 Epigenetics Bromodomain 0 12 Nov 2020
MG-277 GSPT1 Other Translation Termination Factor 0 24 Nov 2020
TAK-243 UBA1 Other post-translational modification Ubiquitin-conjugating enzyme 0 17 Nov 2020
AZ-960 JAK2 Protein kinase Tyrosine kinase 0 27 Nov 2020
GSK2194069 FASN Lipid metabolism Synthase 0 21 Oct 2020
GSK2973980A DGAT1 Other Diacylglycerol O-acyltransferase 0 23 Oct 2020
GNF-5837 TRKA, TRKB, TRKC Protein kinase Tyrosine kinase 0 17 Nov 2020
THAL-SNS-032 CDK9, CDK10 Protein kinase cyclin dependent kinase 0 12 Nov 2020
dTAG-13 FKBP1A (F36V mutant) Other Prolyl Isomerase 0 14 Nov 2020
EML631 SPIN1 Transcription factor Chromatin regulator 0 17 Jun 2020
GNE-781 CREBBP/EP300 Epigenetics Bromodomain 0 25 Nov 2020
G749 FLT3 Protein kinase Tyrosine kinase 0 27 Nov 2020
QC6352 KDM4C Epigenetics Protein Demethylase 0 22 Oct 2020
Capmatinib MET Protein kinase receptor tyrosine kinase 0 26 Oct 2020
BSJ-03-123 CDK6 Protein kinase Ser/Thr Protein Kinase 0 12 Nov 2020
PF-06869206 NaPi2A Ion channel type II sodium-phosphate cotransporter 0 20 Oct 2020
Asciminib BCR-ABL Protein kinase Tyrosine kinase 0 23 Nov 2020
AMG 337 MET Protein kinase Tyrosine kinase 0 26 Nov 2020
SB-612111 OPRL1 GPCR Opioid Receptor 0 23 Oct 2020
TH1760 NUDT15 Epigenetics Nudix Hydrolase 0 16 Nov 2020
TP-024 GPR52 GPCR A orphan G protein-coupled receptor 0 29 May 2020
dTRIM24 TRIM24 Transcription factor tripartite motif family 0 13 Nov 2020