ARCC-4

Degrader (PROTAC) of AR

Structure

SERP Rating

In Cells

(1 ratings)

In Model Organisms

(0 ratings)

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Probe ARCC-4 is in the process of SERP review.

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Information

Degrader (PROTAC)

> 50 nM

DOI - 10.1038/s42003-018-0105-8

Probe Availability:

MedChemExpress
MCULE

In Vitro Validations

No in Vitro Validations

In Cell Validations

In Vivo Data

No in Vivo Validations

Off-Target Selectivity Assesments

Probe Selectivity in Cell:

@ 1 uM ARCC-4 had no effect on glucocorticoid receptor and estrogen receptor levels, while there was a modest decrease in progesterone receptor (PR) A and B levels in T47D cells.

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SERP ratings and comments

SERP Ratings

In Cell Rating

(last updated: 9 Feb 2021 )