AM-6226

Full Agonist of FFAR1

Structure

Information

Protein target names: FFAR1

Mechanism of action: Full Agonist

Recommended in-cell concentration:
up to 10 uM

In Vitro Validations

Uniprot ID: O14842
Target Class: GPCR
Target SubClass: Free fatty acid receptor
PDB ID for probe-target interaction (3D structure): --
Structure-activity relationship: yes
Target aliases:
Free fatty acid receptor 1, GPR40, FFAR1, FFAR1_HU ...

In Cell Validations

In Vivo Data

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SERP ratings and comments


SERP Ratings

In Cell Rating
In Model Organisms

SERP Comments:

Although the authors provide off-target assessment within the family, off-target evaluation of other GPCRs, ion channels, transporters, kinases and similar are not provided. Without such information it is impossible to use this probe with confidence in vitro or in vivo

(last updated: 22 Nov 2021 )

SERP Ratings

In Cell Rating
In Model Organisms

(last updated: 24 Nov 2021 )