AK-42

AK-42 : Inhibitor of CLCN2

Structure

SERP Rating

Probe AK-42 is in the process of SERP review.

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Information

CLCN2

Inhibitor

Probe Availability:

DC Chemicals
MedKoo

In Vitro Validations

No in Vitro Validations

In Cell Validations

In Vivo Data

No in Vivo Validations

Off-Target Selectivity Assesments

Probe Selectivity in Vitro:

AK-42 displays unprecedented selectivity (>1,000-fold) over CLC-1, the closest CLC-2 homolog, and exhibits no off-target engagement against a panel of 61 common channels, receptors, and transporters expressed in brain tissue.

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SERP ratings and comments

No SERP comments found for AK-42