2-hydroxymyristic acid
Unsuitables - unsuitable to be used as a chemical probe
Structure
This is unsuitable as a chemical probe: While this
compound has been used to interrogate specific protein
targets, it is not a chemical probe and should not be used
in assays that depend on a potent and selective modulator
of the protein.
Non selective compound
In 2019 Kallemeijn W et al reported that at 100 μM 2-hydroxymyristic acid did not inhibit recombinant NMT1 or inhibit cellular N-myristoylation by a wide range of assays, and thus it was invalidated as an NMT inhibitor (PMID: 31006618).