KU-0058948
Unsuitables - unsuitable to be used as a chemical probe
Structure
This is unsuitable as a chemical probe: While this
compound has been used to interrogate specific protein
targets, it is not a chemical probe and should not be used
in assays that depend on a potent and selective modulator
of the protein.
Non selective compound
Intended target=PARPs; KU-0058948 is a relatively non-selective PARP inhibitor with insufficient potency, selectivity or validation in cells to be a chemical probe.