D-NMAPPD
Unsuitables - unsuitable to be used as a chemical probe
Structure
This is unsuitable as a chemical probe: While this
compound has been used to interrogate specific protein
targets, it is not a chemical probe and should not be used
in assays that depend on a potent and selective modulator
of the protein.
Non selective compound
Recent data reported by Kallemeijn W et al 2019 invalidate D-NMAPPD as an NMT inhibitor. Data include direct evidence for failed target engagement in a selection of cell lines previously reported using D-NMAPPD as a putative NMT inhibitor (PMID: 31006618).
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