PFI-1

Protein target name: 
BRD2, BRD3, BRD4, BRDT
Mechanism of action: 
Inhibitor

Primary Reference

SAB Comments

This probe meets SGC probe criteria.

This probe meets minimal criteria for use in both cellular and in vivo assays.

Plasma protein binding information relevant to its use: PFI-1 displayed an IC50 of 1.89 uM (n=6) in LPS-stimulated PBMCs with an IL-6 readout, using RPMI media containing 5% FBS (see PMID: 23095041).